80电影天堂网,少妇高潮一区二区三区99,jαpαnesehd熟女熟妇伦,无码人妻精品一区二区蜜桃网站

搜索:  
Probing Molecular and Surface Interactions of Mussel Adhesive Proteins by Using Surface Forces Apparatus  
Probing Molecular and Surface Interactions of Mussel Adhesive Proteins by Using Surface Forces Apparatus
資料類型: PDF文件
關(guān)鍵詞: molecular  interactions  surface  forces  apparatus  mussel  adhesive  
proteins  
資料大?。?/td> 111K
所屬學(xué)科: 分子表征
來源: 第六屆亞歐研討會上處理和性能增強(qiáng)聚合物會議文集(2013.6.2-6 武漢)
簡介:
Musselssurviveinturbulentseabyrobustunderwateradhesiontoallkindsofwaveandwind-sweptsubstrata,aswellashighlystiffandhighlyextensiblesurfacecoatingsusingaproteinaceousbyssus.Suchremarkablefeaturesmakethebyssusasourceofinspirationforthedevelopmentofnoveladhesives,coatingsandbiomaterialswhichcanbeintroducedinasimilarlyturbulentaqueousenwronmentinthehumanbody.Themusselbyssusresemblesabundleofthreadstippedwithadhesiveplaquesandcontainsroughly25-30differentproteins.Understandingtheadhesionandcohesionmechanismoftheseproteinsisofbothfundamentalandpracticalimportanceinthedevelopmentofbiomedicaladhesivesandcoatings.Ourgrouphasendeavoredtoinvestigatethemolecularandsurfaceinteractionmechanismsofmusseladhesiveproteinsbyapplyingamolecularforceprobetechnique-SurfaceForcesApparatus(SFA).TheSFAstudieswereperformedinvariousconfigurations:(i)aproteinfilmagainstdifferentsubstrata,(ii)aproteinfilmagainstanothersurfaceofthesameordifferentprotein,and(iii)proteinsolutionsconfinedbetweendifferentsubstrata.Itwasfoundthattheadhesionandcohesionofmusselfootproteinsarecriticallyrelatedtothemodifiedprominentaminoacid,L-3,4-dihydroxyphenylalanine(DOPA)orC2_mannosyl_7_hydroxytryptophan(Man70HTrp).Formusseladhesiontovarioussubstrata,DOPAplaystheimportantroleviadiverseinteractionsincludinghydrogenbonding,metalcoordination,cation-7rinteractions.DOPA-richproteinsmfp-3andmfp-5playamajorroleintheadhesionatplaque-substratainterfaces.DOPAalsocontributessignificantlytotheproteincohesionviametalcoordination(e.g.,DOPA_Ca2+,DOPA_Fe3+),cation-7rinteractions(e.g.,DOPA-Lys+).Ourresultsprovidenewinsightsintothedevelopmentofbiomimeticunderwateradhesivesandcoatingsforbiomedicalapplications.
作者: Q. Y. Lu, H. B. Zeng
上傳時間: 2013-06-25 11:34:36
下載次數(shù): 1
消耗積分: 2  
立即下載:
1人
1人
1人
友情提示:下載后對該資源進(jìn)行評論,即可獎勵2分。
報告錯誤:  1.下載無效  2. 資料明顯無價值  3. 資料重復(fù)存在

相關(guān)評論 共有0人發(fā)表評論 更多評論
你還沒有登錄,無法發(fā)表評論,請首先 登錄 注冊
免責(zé)聲明:本站部分資源由網(wǎng)友推薦,來自互聯(lián)網(wǎng),版權(quán)屬于原版權(quán)人,如果不慎侵犯到您的權(quán)利,敬請告知,我們會在第一時間撤除。本站中各網(wǎng)友的評論只代表其個人觀點(diǎn),不代表本站同意其觀點(diǎn)。